Can tooth enamel regrow ?
Dental caries are one of the most common and widespread persistent diseases today. It became a major oral health problem in many countries of the world. Getting rid of caries isn’t an easy thing especially when you know that a tooth does not regenerate itself. An enamel destruction is normally not reversible.
Participate in Dental Health Care and Cure Cavities
Researchers at the University of Washington have focused on this topic and tried to develop technologies about Dental Health Care that rebuild teeth and induce the regrowth of enamel and preserve tooth structure.
The study published in the journal ACS Biomaterials Science and Engineering on the 9th March 2018 demonstrates that many peptidedomains derived from native protein amelogenin can be used to construct a mineral layer on damaged human enamel in vitro. [1]
Could a revolutionary method make that possible ?
Those peptides can feasably promote mineralization. They attach to the teeth « biomineralise », recruit calcium and phosphate ions and create a new layer. After just one use, we can reach at least 10 ?m of new remineralized enamel, that’s a truly revolution in curing cavities.
The peptide-guided remineralization approach idea came from the body’s own natural tooth-forming proteins ; in fact the amelogenin protein is crucial in enamel formation.
Is this the end of tooth decay ?
This may sound too good to be true because many alternative ways to rebuild the enamel have been proposed in the past with moderate success but this time, researchers have finally found a natural product which can be a foundation for future development of biomimetic products and treatments for dental health care. It promises to transform the approach to cure cavities forever.
Litterature :
[1] Sami Dogan, Hanson Fong, Deniz T. Yucesoy, Timothee Cousin, Carolyn Gresswell, Sefa Dag, Greg Huang, Mehmet Sarikaya . Biomimetic Tooth Repair: Amelogenin-derived peptide enables in vitro remineralization of human enamel. ACS Biomaterials Science & Engineering.F